Drug Dosing Is Major Cause Of Errors in U.S. Hospitals
By Stacy Foster

Incorrect administration of drugs is a significant cause of errors in hospitals and poses an especially serious risk to children and emergency-room visitors, according to a new study.

For children, the problem often stems from a miscalculation when converting weight from pounds to kilograms, leading to improper dosing. In emergency rooms, the combination of interruptions and multiple tasks prompts errors.

Although most hospital medication mistakes are discovered and corrected quickly, some are fatal, said the study, to be released Wednesday by the U.S. Pharmacopeia's Center for the Advancement of Patient Safety. The study found that 2,539, or 2.4%, of the 105,603 medication errors documented by American hospitals participating in the study in 2001 resulted in patient injury or fatality. Of these, 353 required initial or prolonged hospitalization, 70 prompted intervention to sustain life and 14 resulted in death.

U.S. Pharmacopeia represents the drug industry, doctors, health-care associations, academia, the U.S. government, and consumer organizations and works to establish standards and practices for the use of pharmaceuticals.

Data for the study were voluntarily provided by 368 health-care facilities across the country and compiled by Medmarx, a database administered by U.S. Pharmacopeia.

The study attributes the errors largely to workload increases for doctors and nurses. Distractions were the most common cause of error but were often combined with other factors. Inexperienced or inadequate staff accounted for about 43% of the factors contributing to errors, an increase from 33% in 2000 and 27% in 1999.

"We've heard a lot about the nursing shortage, but what we're seeing is there are errors from shortage of respiratory therapists or pharmacists," said Diane Cousins, vice president of the Center for Advancement of Patient Safety.

Hospitals have come under fire in recent years for not getting their hands around drug-administration errors and the staffing issues that lead to them.

Giving doctors and other health-care professionals greater access to technology and communications tools would help them treat patients more effectively, said Donald Berwick, president of the Institute for Healthcare Improvement at Harvard University.



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