Medical Errors Are Kids' Stuff
Mistakes made in 1 of 16 medication orders

By Edward Edelson

TUESDAY, April 24 (HealthScout) -- Boston Children's Hospital and Massachusetts Hospital for Children are two of the country's best hospitals for young patients. But a study finds that mistakes were made in one of every 16 drugs prescribed for 1,120 children treated in those hospitals during a six-week period in 1999.

"We reviewed 10,778 medication orders and found 616 medication errors (5.7 percent), 115 potential adverse drug reactions (1.1 percent) and 26 adverse drug reactions," says a report in this week's Journal of the American Medical Association.

That error rate is about the same as has been reported in studies of adult patients, says Dr. Rainu Kaushal. She is an instructor in medicine at Harvard Medical School and led the group of researchers. And while none of the mistakes were fatal, "there are a number of close calls or near misses," she says.

The study is important because "this is the first to delve into the issue of pediatric medication errors," says Dr. Gregg S. Meyer, director of the Center for Quality Improvement and Patient Safety at the federal Agency for Healthcare Research and Quality, which helped fund the study.

"The trend thus far is that wherever we have looked for medical errors, we have found them," Meyer says. "The findings documented for adults now are mirrored by the findings for pediatric care."

A report by the Institute of Medicine last year estimated that medication errors cause 7,000 hospital deaths a year. Some experts say the number could be higher.

Breaking the results down by category, the Boston researchers found that most of the errors occurred at the stage when a drug was ordered by a physician. Many of those errors were mistakes in the dosage ordered for the young patient, because drug dosages often are based on the weight of the patient and a child can gain weight quickly. In addition, "pharmacists have to dilute solutions, which are often at adult strengths, and they must divide pills for a young patient," Kaushal says.

Another source of error is understandable, she says: "Children, particularly those who are small and critically ill, cannot communicate well."

The good news is that more than 90 percent of the errors were potentially preventable, and that the hospitals are instituting programs to prevent them, she says. One program is having computerized systems in which doctors enter medication orders. Another is having clinical pharmacists in each ward.

"Physician reviewers judged that computerized physician order entry could potentially have prevented 93 percent and ward-based clinical pharmacists 94 percent of potential adverse drug reactions," the report says.

Other measures include bar-coding medications, with the bar code on the drug matching that worn by the patient; having robotic help in preparing medications; and an automated alert system that would signal when a patient needs a drug and the proper dosage for the patient, Kaushal says.

"In both these hospitals, we have been very active in planning ways to make the hospital more safe for the patients," she says. "We are investing in computerized systems, ward-based pharmacists and computerized transcribing."

Meyer says the message of the study is that safety lies "in looking at the entire chain, beginning with the physician ordering the medication to the pharmacist filling the order to the delivery of the medication to the patient. Each step is fraught with potential hazard. The real issue is not to look at any individual step, but to look at the entire system and where the opportunities for improvement in providing safe care lie."

Another innovation being studied is the use of "smart" intravenous delivery systems, programmed to deliver the correct dose of an intravenous solution. Something as basic as increased staffing and closer coordination between doctors and nurses can also reduce errors, Kaushal says.

What to do

Parents have a role to play in protecting their children, Kaushal says. "Parents can help by bringing in adequate lists of medications, or the medications themselves," she says. "They can help by asking questions about medications, if they don't understand why the child is taking a medication. It should be a partnership with the health-care providers."

For more information on medical errors and how to prevent them from happening to you, check out theAgency for Healthcare Research and Qualityandhere is the report to the president on medical errors from the Quality in the Health Care Industry task force.



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